CPU: 2.4 GHz dual core Intel or AMD processor
RAM: 1GB of system memory
Graphics: DirectX 10 compatible card with 512 MB RAM. Nvidia 8-series or AMD Radeon 3000 series graphics cards.
Operating system: Windows Vista
DirectX compatible sound card
10 GB of hard drive space
Önerilen Sistem Gereksinimleri
CPU: 2.6 GHz quad core Intel or AMD processor, Core i5 or Phenom X2
RAM: 2GB
Graphics: DirectX 10 compatible card with 1GB of video memory, Nvidia 400-series or AMD 5000-series.
Operating system: Windows 7
DirectX compatible sound card
10 GB of hard drive space
Hitman: Absolution, Windows XP işletim sistemi yüklü PClerde çalışmıyor.Çalışmamasının nedeni ise Windows XP'nin DX 11 desteklememesi.